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PDE5 Inhibitors as Potential Tools in the Treatment of Cystic Fibrosis

Despite great advances in the understanding of the genetics and pathophysiology of cystic fibrosis (CF), there is still no cure for the disease. Using phosphodiesterase type 5 (PDE5) inhibitors, we and others have provided evidence of rescued F508del-CFTR trafficking and corrected deficient chloride...

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Sonraí Bibleagrafaíochta
Main Authors: Noel, Sabrina, Dhooghe, Barbara, Leal, Teresinha
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Research Foundation 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3444771/
https://ncbi.nlm.nih.gov/pubmed/23024633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2012.00167
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