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Dynamics of epigenetic regulation at the single-cell level

Chromatin regulators play a major role in establishing and maintaining gene expression states. Yet how they control gene expression in single cells, quantitatively and over time, remains unclear. We used time-lapse microscopy to analyze the dynamic effects of four silencers associated with diverse m...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Bintu, Lacramioara, Yong, John, Antebi, Yaron E., McCue, Kayla, Kazuki, Yasuhiro, Uno, Narumi, Oshimura, Mitsuo, Elowitz, Michael B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5108652/
https://ncbi.nlm.nih.gov/pubmed/26912859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aab2956
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