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Use of ferrous iron by metallo-β-lactamases
Metallo-β-lactamases (MBLs) catalyse the hydrolysis of almost all β-lactam antibacterials including the latest generation carbapenems and are a growing worldwide clinical problem. It is proposed that MBLs employ one or two zinc ion cofactors in vivo. Isolated MBLs are reported to use transition meta...
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| Veröffentlicht in: | J Inorg Biochem |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Elsevier
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5108564/ https://ncbi.nlm.nih.gov/pubmed/27498591 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinorgbio.2016.07.013 |
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