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AKT activation controls cell survival in response to HDAC6 inhibition
HDAC6 is emerging as an important therapeutic target for cancer. We investigated mechanisms responsible for survival of tumor cells treated with a HDAC6 inhibitor. Expression of the 20 000 genes examined did not change following HDAC6 treatment in vivo. We found that HDAC6 inhibition led to an incre...
में बचाया:
| में प्रकाशित: | Cell Death Dis |
|---|---|
| मुख्य लेखकों: | , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Nature Publishing Group
2016
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5108334/ https://ncbi.nlm.nih.gov/pubmed/27362804 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.180 |
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