IIp45 Inhibits Cell Migration through Inhibition of HDAC6

IIp45 (aka MIIP) is a newly discovered gene whose protein product inhibits cell migration. HDAC6 is a class IIb deacetylase that specifically deacetylates α-tubulin, modulates microtubule dynamics, and promotes cell migration. A yeast two-hybrid assay using IIp45 as bait identified HDAC6 protein as...

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Detalhes bibliográficos
Main Authors: Wu, Ying, Song, Sonya W., Sun, Jiyuan, Bruner, Janet M., Fuller, Gregory N., Zhang, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Molecular Basis of Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823495/
https://ncbi.nlm.nih.gov/pubmed/20008322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.063354
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