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IIp45 Inhibits Cell Migration through Inhibition of HDAC6
IIp45 (aka MIIP) is a newly discovered gene whose protein product inhibits cell migration. HDAC6 is a class IIb deacetylase that specifically deacetylates α-tubulin, modulates microtubule dynamics, and promotes cell migration. A yeast two-hybrid assay using IIp45 as bait identified HDAC6 protein as...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2823495/ https://ncbi.nlm.nih.gov/pubmed/20008322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.063354 |
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