Enhanced cAMP-stimulated protein kinase A activity in human fibrolamellar hepatocellular carcinoma

BACKGROUND: Fibrolamellar hepatocellular carcinoma (FL-HCC) affects children without underlying liver disease. A consistent mutation in FL-HCCs leads to fusion of the genes encoding a heat shock protein (DNAJB1) and the catalytic subunit of protein kinase A (PRKACA). We sought to characterize the re...

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Publicat a:Pediatr Res
Autors principals: Riggle, Kevin M., Riehle, Kimberly J., Kenerson, Heidi L., Turnham, Rigney, Homma, Miwako K., Kazami, Machiko, Samelson, Bret, Bauer, Renay, McKnight, G. Stanley, Scott, John D., Yeung, Raymond S.
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5105330/
https://ncbi.nlm.nih.gov/pubmed/27027723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/pr.2016.36
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