Neurotensin as a source of cyclic AMP and co-mitogen in fibrolamellar hepatocellular carcinoma

Fibrolamellar hepatocellular carcinomas (FL-HCCs) possess a unique mutation that encodes a chimeric form of protein kinase A (DNAJ-PKAc), which includes a chaperonin binding domain. DNAJ-PKAc retains most of the biochemical properties of the native enzyme, however, and activity remains dependent on...

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Pubblicato in:Oncotarget
Autori principali: Riehle, Kimberly J., Kenerson, Heidi L., Riggle, Kevin M., Turnham, Rigney, Sullivan, Kevin, Bauer, Renay, Scott, John D., Yeung, Raymond S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2019
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6707953/
https://ncbi.nlm.nih.gov/pubmed/31489118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27149
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