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Mechanisms of Insertion of dCTP and dTTP Opposite the DNA Lesion O(6)-Methyl-2′-deoxyguanosine by Human DNA Polymerase η
O(6)-Methyl-2′-deoxyguanosine (O(6)-MeG) is a ubiquitous DNA lesion, formed not only by xenobiotic carcinogens but also by the endogenous methylating agent S-adenosylmethionine. It can introduce mutations during DNA replication, with different DNA polymerases displaying different ratios of correct o...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5104950/ https://ncbi.nlm.nih.gov/pubmed/27694439 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.755462 |
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