Llwytho...

DCTPP1 prevents a mutator phenotype through the modulation of dCTP, dTTP and dUTP pools

To maintain dNTP pool homeostasis and preserve genetic integrity of nuclear and mitochondrial genomes, the synthesis and degradation of DNA precursors must be precisely regulated. Human all-alpha dCTP pyrophosphatase 1 (DCTPP1) is a dNTP pyrophosphatase with high affinity for dCTP and 5′-modified dC...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Mol Life Sci
Prif Awduron: Martínez-Arribas, Blanca, Requena, Cristina E., Pérez-Moreno, Guiomar, Ruíz-Pérez, Luis M., Vidal, Antonio E., González-Pacanowska, Dolores
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer International Publishing 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7162842/
https://ncbi.nlm.nih.gov/pubmed/31377845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-019-03250-x
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