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Resveratrol reverses P-glycoprotein-mediated multidrug resistance of U2OS/ADR cells by suppressing the activation of the NF-κB and p38 MAPK signaling pathways

The present study aimed to investigate the reversal effect of resveratrol on the phenomenon of multidrug resistance in U2OS/adriamycin (ADR) cells and to clarify the molecular mechanisms. To examine the cell survival and half-inhibitory concentration (IC(50)) of ADR in U2OS and U2OS/ADR cells, 3-(4,...

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Publicat a:Oncol Lett
Autors principals: Zhang, Rui, Lu, Ming, Zhang, Zhen, Tian, Xiliang, Wang, Shouyu, Lv, Decheng
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5104249/
https://ncbi.nlm.nih.gov/pubmed/27895784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2016.5136
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