Lipopolysaccharide-Binding Protein Downregulates Fractalkine through Activation of p38 MAPK and NF-κB

BACKGROUND: LBP and fractalkine are known to be involved in the pathogenesis of ARDS. This study investigated the relationship between LBP and fractalkine in LPS-induced A549 cells and rat lung tissue in an ARDS rat model. METHODS: A549 cells were transfected with LBP or LBP shRNA plasmid DNA or pre...

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Detalhes bibliográficos
Publicado no:Mediators Inflamm
Main Authors: Huang, Xia, Zeng, Yi, Jiang, Yujie, Qin, Yueqiu, Luo, Weigui, Xiang, Shulin, Sooranna, Suren R., Pinhu, Liao
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5467387/
https://ncbi.nlm.nih.gov/pubmed/28634422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/9734837
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