NAMPT-mediated NAD(+) biosynthesis is essential for vision in mice

Photoreceptor death is the endpoint of many blinding diseases. Identifying unifying pathogenic mechanisms in these diseases may offer global approaches for facilitating photoreceptor survival. We found that rod or cone photoreceptor-specific deletion of nicotinamide phosphoribosyltransferase (Nampt)...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Lin, Jonathan B., Kubota, Shunsuke, Ban, Norimitsu, Yoshida, Mitsukuni, Santeford, Andrea, Sene, Abdoulaye, Nakamura, Rei, Zapata, Nicole, Kubota, Miyuki, Tsubota, Kazuo, Yoshino, Jun, Imai, Shin-ichiro, Apte, Rajendra S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5104206/
https://ncbi.nlm.nih.gov/pubmed/27681422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.08.073
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