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IL10-driven STAT3 signalling in senescent macrophages promotes pathological eye angiogenesis
Macrophage dysfunction plays a pivotal role during neovascular proliferation in diseases of ageing including cancers, atherosclerosis and blinding eye disease. In the eye, choroidal neovascularization (CNV) causes blindness in patients with age-related macular degeneration (AMD). Here we report that...
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| Опубликовано в: : | Nat Commun |
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| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4918330/ https://ncbi.nlm.nih.gov/pubmed/26260587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8847 |
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