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IL10-driven STAT3 signalling in senescent macrophages promotes pathological eye angiogenesis
Macrophage dysfunction plays a pivotal role during neovascular proliferation in diseases of ageing including cancers, atherosclerosis and blinding eye disease. In the eye, choroidal neovascularization (CNV) causes blindness in patients with age-related macular degeneration (AMD). Here we report that...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4918330/ https://ncbi.nlm.nih.gov/pubmed/26260587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8847 |
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