Impaired autophagy in macrophages promotes inflammatory eye disease

Autophagy is critical for maintaining cellular homeostasis. Organs such as the eye and brain are immunologically privileged. Here, we demonstrate that autophagy is essential for maintaining ocular immune privilege. Deletion of multiple autophagy genes in macrophages leads to an inflammation-mediated...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Santeford, Andrea, Wiley, Luke A., Park, Sunmin, Bamba, Sonya, Nakamura, Rei, Gdoura, Abdelaziz, Ferguson, Thomas A., Rao, P. Kumar, Guan, Jun-Lin, Saitoh, Tatsuya, Akira, Shizuo, Xavier, Ramnik, Virgin, Herbert W., Apte, Rajendra S.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Basic Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5066937/
https://ncbi.nlm.nih.gov/pubmed/27463423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2016.1207857
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