Impaired autophagy in macrophages promotes inflammatory eye disease

Autophagy is critical for maintaining cellular homeostasis. Organs such as the eye and brain are immunologically privileged. Here, we demonstrate that autophagy is essential for maintaining ocular immune privilege. Deletion of multiple autophagy genes in macrophages leads to an inflammation-mediated...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Autophagy
Päätekijät: Santeford, Andrea, Wiley, Luke A., Park, Sunmin, Bamba, Sonya, Nakamura, Rei, Gdoura, Abdelaziz, Ferguson, Thomas A., Rao, P. Kumar, Guan, Jun-Lin, Saitoh, Tatsuya, Akira, Shizuo, Xavier, Ramnik, Virgin, Herbert W., Apte, Rajendra S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Taylor & Francis 2016
Aiheet:
Basic Research Papers
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5066937/
https://ncbi.nlm.nih.gov/pubmed/27463423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2016.1207857
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