Impaired cholesterol efflux in senescent macrophages promotes age-related macular degeneration

Pathologic angiogenesis mediated by abnormally polarized macrophages plays a central role in common age-associated diseases such as atherosclerosis, cancer and macular degeneration. Here we demonstrate that abnormal polarization in older macrophages is caused by programmatic changes that lead to red...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Sene, Abdoulaye, Khan, Aslam A., Cox, Douglas, Nakamura, Rei E.I., Santeford, Andrea, Kim, Bryan M., Sidhu, Rohini, Onken, Michael D., Harbour, J. William, Haqbi-Levi, Shira, Chowers, Itay, Edwards, Peter A., Baldan, Angel, Parks, John S., Ory, Daniel S, Apte, Rajendra S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3640261/
https://ncbi.nlm.nih.gov/pubmed/23562078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2013.03.009
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky