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The importance of NAMPT/NAD/SIRT1 in the systemic regulation of metabolism and aging
Aging is associated with a variety of pathophysiological changes, including development of insulin resistance, progressive decline in β-cell function, and chronic inflammation, all of which affect metabolic homeostasis in response to nutritional and environmental stimuli. SIRT1, the mammalian nicoti...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3819727/ https://ncbi.nlm.nih.gov/pubmed/24003918 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/dom.12171 |
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