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The NAD World: A new systemic regulatory network for metabolism and aging – Sirt1, systemic NAD biosynthesis, and their importance
For the past several years, it has been demonstrated that the NAD-dependent protein deacetylase Sirt1 and nicotinamide phosphoribosyltransferase (Nampt)-mediated systemic NAD biosynthesis together play a critical role in the regulation of metabolism and possibly aging in mammals. Based on our recent...
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| Formato: | Artigo |
| Idioma: | Inglês |
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2009
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2734380/ https://ncbi.nlm.nih.gov/pubmed/19130305 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12013-008-9041-4 |
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