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Dissecting Systemic Control of Metabolism and Aging in the NAD World: The Importance of SIRT1 and NAMPT-mediated NAD Biosynthesis

Many countries are facing social and economic problems due to increased elderly demographics. With these demands, it is now critical to understand the fundamental regulatory mechanism for aging and longevity in mammals. Our studies on the mammalian NAD-dependent deacetylase SIRT1 and nicotinamide ph...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser: Imai, Shin-ichiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3104082/
https://ncbi.nlm.nih.gov/pubmed/21550345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2011.04.060
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