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Total Synthesis, Structure, and Biological Activity of Adenosylrhodibalamin, the Non‐Natural Rhodium Homologue of Coenzyme B(12)

B(12) is unique among the vitamins as it is biosynthesized only by certain prokaryotes. The complexity of its synthesis relates to its distinctive cobalt corrin structure, which is essential for B(12) biochemistry and renders coenzyme B(12) (AdoCbl) so intriguingly suitable for enzymatic radical rea...

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Dettagli Bibliografici
Pubblicato in:Angew Chem Int Ed Engl
Autori principali: Widner, Florian J., Lawrence, Andrew D., Deery, Evelyne, Heldt, Dana, Frank, Stefanie, Gruber, Karl, Wurst, Klaus, Warren, Martin J., Kräutler, Bernhard
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5103170/
https://ncbi.nlm.nih.gov/pubmed/27355790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201603738
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