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Total Synthesis, Structure, and Biological Activity of Adenosylrhodibalamin, the Non‐Natural Rhodium Homologue of Coenzyme B(12)

B(12) is unique among the vitamins as it is biosynthesized only by certain prokaryotes. The complexity of its synthesis relates to its distinctive cobalt corrin structure, which is essential for B(12) biochemistry and renders coenzyme B(12) (AdoCbl) so intriguingly suitable for enzymatic radical rea...

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Détails bibliographiques
Publié dans:Angew Chem Int Ed Engl
Auteurs principaux: Widner, Florian J., Lawrence, Andrew D., Deery, Evelyne, Heldt, Dana, Frank, Stefanie, Gruber, Karl, Wurst, Klaus, Warren, Martin J., Kräutler, Bernhard
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5103170/
https://ncbi.nlm.nih.gov/pubmed/27355790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201603738
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