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Plexin C1 deficiency permits synaptotagmin 7–mediated macrophage migration and enhances mammalian lung fibrosis

Pulmonary fibrosis is a progressive and often fatal condition that is believed to be partially orchestrated by macrophages. Mechanisms that control migration of these cells into and within the lung remain undefined. We evaluated the contributions of the semaphorin receptor, plexin C1 (PLXNC1), and t...

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Bibliografiske detaljer
Udgivet i:FASEB J
Main Authors: Peng, Xueyan, Moore, Meagan, Mathur, Aditi, Zhou, Yang, Sun, Huanxing, Gan, Ye, Herazo-Maya, Jose D., Kaminski, Naftali, Hu, Xinyuan, Pan, Hongyi, Ryu, Changwan, Osafo-Addo, Awo, Homer, Robert J., Feghali-Bostwick, Carol, Fares, Wassim H., Gulati, Mridu, Hu, Buqu, Lee, Chun-Geun, Elias, Jack A., Herzog, Erica L.
Format: Artigo
Sprog:Inglês
Udgivet: Federation of American Societies for Experimental Biology 2016
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5102121/
https://ncbi.nlm.nih.gov/pubmed/27609773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201600373R
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