Extracellular Mitochondrial DNA Is Generated by Fibroblasts and Predicts Death in Idiopathic Pulmonary Fibrosis

Rationale: Idiopathic pulmonary fibrosis (IPF) involves the accumulation of α-smooth muscle actin–expressing myofibroblasts arising from interactions with soluble mediators such as transforming growth factor-β1 (TGF-β1) and mechanical influences such as local tissue stiffness. Whereas IPF fibroblast...

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Bibliografiske detaljer
Udgivet i:Am J Respir Crit Care Med
Main Authors: Ryu, Changwan, Sun, Huanxing, Gulati, Mridu, Herazo-Maya, Jose D., Chen, Yonglin, Osafo-Addo, Awo, Brandsdorfer, Caitlin, Winkler, Julia, Blaul, Christina, Faunce, Jaden, Pan, Hongyi, Woolard, Tony, Tzouvelekis, Argyrios, Antin-Ozerkis, Danielle E., Puchalski, Jonathan T., Slade, Martin, Gonzalez, Anjelica L., Bogenhagen, Daniel F., Kirillov, Varvara, Feghali-Bostwick, Carol, Gibson, Kevin, Lindell, Kathleen, Herzog, Raimund I., Dela Cruz, Charles S., Mehal, Wajahat, Kaminski, Naftali, Herzog, Erica L., Trujillo, Glenda
Format: Artigo
Sprog:Inglês
Udgivet: American Thoracic Society 2017
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5754440/
https://ncbi.nlm.nih.gov/pubmed/28783377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201612-2480OC
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