Plexin C1 deficiency permits synaptotagmin 7–mediated macrophage migration and enhances mammalian lung fibrosis

Pulmonary fibrosis is a progressive and often fatal condition that is believed to be partially orchestrated by macrophages. Mechanisms that control migration of these cells into and within the lung remain undefined. We evaluated the contributions of the semaphorin receptor, plexin C1 (PLXNC1), and t...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Peng, Xueyan, Moore, Meagan, Mathur, Aditi, Zhou, Yang, Sun, Huanxing, Gan, Ye, Herazo-Maya, Jose D., Kaminski, Naftali, Hu, Xinyuan, Pan, Hongyi, Ryu, Changwan, Osafo-Addo, Awo, Homer, Robert J., Feghali-Bostwick, Carol, Fares, Wassim H., Gulati, Mridu, Hu, Buqu, Lee, Chun-Geun, Elias, Jack A., Herzog, Erica L.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5102121/
https://ncbi.nlm.nih.gov/pubmed/27609773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201600373R
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