Netrin-1 regulates fibrocyte accumulation in the decellularized fibrotic scleroderma lung microenvironment and in bleomycin induced pulmonary fibrosis

OBJECTIVES: Fibrocytes are collagen-producing leukocytes that accumulate in Scleroderma-associated interstitial lung disease (SSc-ILD) via unknown mechanisms. The extracellular matrix (ECM) influences cellular phenotypes. However, a relationship between the lung ECM and fibrocytes in Scleroderma has...

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Detalhes bibliográficos
Publicado no:Arthritis Rheumatol
Main Authors: Sun, Huanxing, Zhu, Yangyang, Pan, Hongyi, Chen, Xiaosong, Balestrini, Jenna L., Lam, TuKiet T., Kanyo, Jean E., Eichmann, Anne, Gulati, Mridu, Fares, Wassim H., Bai, Hanwen, Feghali-Bostwick, Carol A., Gan, Ye, Peng, Xueyan, Moore, Meagan W., White, Eric S., Sava, Parid, Gonzalez, Anjelica L., Cheng, Yuwei, Niklason, Laura E., Herzog, Erica L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5547894/
https://ncbi.nlm.nih.gov/pubmed/26749424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.39575
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