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Antigen specific development of mucosal Foxp3+RORγt+ T cells from regulatory T cell precursors

Foxp3+RORγt+ T cells have recently been characterized as an immunoregulatory population highly enriched in the colon lamina propria. However, their developmental origin and relation to RORγt− Treg and T(H)17 cells remains unclear. Here, we use a fixed TCRβ system to show that the TCR repertoire of t...

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Bibliografske podrobnosti
izdano v:J Immunol
Main Authors: Solomon, Benjamin D., Hsieh, Chyi-Song
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5101183/
https://ncbi.nlm.nih.gov/pubmed/27671109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601217
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