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Antigen-specific peripheral shaping of the natural regulatory T cell population

Although regulatory T (T reg) cells are thought to develop primarily in the thymus, the peripheral events that shape the protective T reg cell population are unclear. We analyzed the peripheral CD4(+) T cell receptor (TCR) repertoire by cellular phenotype and location in mice with a fixed TCRβ chain...

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Detalhes bibliográficos
Main Authors: Lathrop, Stephanie K., Santacruz, Nicole A., Pham, Dominic, Luo, Jingqin, Hsieh, Chyi-Song
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605228/
https://ncbi.nlm.nih.gov/pubmed/19064700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20081359
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