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Antigen exposure shapes the ratio between antigen-specific Tregs and conventional T cells in human peripheral blood
The T-cell receptor (TCR) is required for maturation and function of regulatory T cells (Tregs), but the ligand specificities of Tregs outside the context of transgenic TCRs are largely unknown. Using peptide–MHC tetramers, we isolated rare specific Foxp3(+) cells directly ex vivo from adult periphe...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5068288/ https://ncbi.nlm.nih.gov/pubmed/27681619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1611723113 |
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