Peripheral tolerance can be modified by altering KLF2-regulated Treg migration

Tregs are essential for maintaining peripheral tolerance, and thus targeting these cells may aid in the treatment of autoimmunity and cancer by enhancing or reducing suppressive functions, respectively. Before these cells can be harnessed for therapeutic purposes, it is necessary to understand how t...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Pabbisetty, Sudheer K., Rabacal, Whitney, Volanakis, Emmanuel J., Parekh, Vrajesh V., Olivares-Villagómez, Danyvid, Cendron, Delphine, Boyd, Kelli L., Van Kaer, Luc, Sebzda, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987800/
https://ncbi.nlm.nih.gov/pubmed/27462110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1605849113
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