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CD28 facilitates the generation of Foxp3(−) cytokine responsive regulatory T cell precursors
The T cell co-stimulatory molecule CD28 plays an important role in the thymic generation of Foxp3(+) regulatory T (Treg) cells essential for the maintenance of self-tolerance. Here, we show that a cell-intrinsic signal from CD28 is involved in the generation of cytokine-responsive Foxp3(−) precursor...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2874117/ https://ncbi.nlm.nih.gov/pubmed/20421644 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000019 |
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