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Generation of Foxp3(+)CD25(−) Regulatory T-Cell Precursors Requires c-Rel and IκB(NS)

Next to the classical developmental route, in which first CD25 and subsequently Foxp3 are induced to generate thymic regulatory T (Treg) cells, an alternative route has been described. This alternative route is characterized by reciprocal induction of Foxp3 and CD25, with CD25 induction being requir...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Schuster, Marc, Plaza-Sirvent, Carlos, Visekruna, Alexander, Huehn, Jochen, Schmitz, Ingo
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6635800/
https://ncbi.nlm.nih.gov/pubmed/31354726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01583
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