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Interferon-β (IFN-β) facilitates neuroantigen-dependent induction of CD25(+) FOXP3(+) regulatory T cells that suppress experimental autoimmune encephalomyelitis (EAE)()

This study introduces a flexible format for tolerogenic vaccination that incorporates IFN-β and neuroantigen (NAg) in the Alum adjuvant. Tolerogenic vaccination required all three components; IFN-β, NAg, and Alum for inhibition of experimental autoimmune encephalomyelitis (EAE) and induction of tole...

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Détails bibliographiques
Publié dans:J Immunol
Auteurs principaux: Wang, Duncheng, Ghosh, Debjani, Islam, S.M. Touhidul, Moorman, Cody D., Thomason, Ashton E., Wilkinson, Daniel S., Mannie, Mark D.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5101178/
https://ncbi.nlm.nih.gov/pubmed/27619998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500411
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