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Depletion of CD4(+) CD25(+) regulatory T cells confers susceptibility to experimental autoimmune encephalomyelitis (EAE) in GM-CSF-deficient Csf2(−/−) mice

Previous studies established that GM-CSF-deficient (Csf2-deficient) mice exhibit profound resistance to experimental autoimmune encephalomyelitis. This study addressed whether the resistance of Csf2-deficient mice was a result of a requirement for GM-CSF in controlling the functional balance between...

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Bibliografski detalji
Izdano u:J Leukoc Biol
Glavni autori: Ghosh, Debjani, Curtis, Alan D., Wilkinson, Daniel S., Mannie, Mark D.
Format: Artigo
Jezik:Inglês
Izdano: Society for Leukocyte Biology 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5014742/
https://ncbi.nlm.nih.gov/pubmed/27256565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.3A0815-359R
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