ROCK signalling induced gene expression changes in mouse pancreatic ductal adenocarcinoma cells

The RhoA and RhoC GTPases act via the ROCK1 and ROCK2 kinases to promote actomyosin contraction, resulting in directly induced changes in cytoskeleton structures and altered gene transcription via several possible indirect routes. Elevated activation of the Rho/ROCK pathway has been reported in seve...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Data
Egile Nagusiak: Rath, Nicola, Kalna, Gabriela, Clark, William, Olson, Michael F.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2016
Gaiak:
Data Descriptor
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5100681/
https://ncbi.nlm.nih.gov/pubmed/27824338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sdata.2016.101
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