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ROCK signalling induced gene expression changes in mouse pancreatic ductal adenocarcinoma cells
The RhoA and RhoC GTPases act via the ROCK1 and ROCK2 kinases to promote actomyosin contraction, resulting in directly induced changes in cytoskeleton structures and altered gene transcription via several possible indirect routes. Elevated activation of the Rho/ROCK pathway has been reported in seve...
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| Publicado no: | Sci Data |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5100681/ https://ncbi.nlm.nih.gov/pubmed/27824338 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sdata.2016.101 |
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