Site Saturation Mutagenesis Applications on Candida methylica Formate Dehydrogenase

In NADH regeneration, Candida methylica formate dehydrogenase (cmFDH) is a highly significant enzyme in pharmaceutical industry. In this work, site saturation mutagenesis (SSM) which is a combination of both rational design and directed evolution approaches is applied to alter the coenzyme specifici...

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Dettagli Bibliografici
Pubblicato in:Scientifica (Cairo)
Autori principali: Özgün, Gülşah P., Ordu, Emel B., Tütüncü, H. Esra, Yelboğa, Emrah, Sessions, Richard B., Gül Karagüler, Nevin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2016
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5099451/
https://ncbi.nlm.nih.gov/pubmed/27847673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/4902450
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