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Crystal structure of a LacY–nanobody complex in a periplasmic-open conformation
The lactose permease of Escherichia coli (LacY), a dynamic polytopic membrane protein, catalyzes galactoside–H(+) symport and operates by an alternating access mechanism that exhibits multiple conformations, the distribution of which is altered by sugar binding. We have developed single-domain camel...
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| 出版年: | Proc Natl Acad Sci U S A |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5098631/ https://ncbi.nlm.nih.gov/pubmed/27791182 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1615414113 |
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