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The immunoglobulin G1 N-glycan composition affects binding to each low affinity Fc γ receptor

Immunoglobulin G1 (IgG1) is the most abundant circulating human antibody and also the scaffold for many therapeutic monoclonal antibodies (mAbs). The destruction of IgG-coated targets by cell-mediated pathways begins with an interaction between the IgG Fc region and multiple varieties of membrane-bo...

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Bibliografski detalji
Izdano u:MAbs
Glavni autori: Subedi, Ganesh P., Barb, Adam W.
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5098437/
https://ncbi.nlm.nih.gov/pubmed/27492264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2016.1218586
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