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The immunoglobulin G1 N-glycan composition affects binding to each low affinity Fc γ receptor
Immunoglobulin G1 (IgG1) is the most abundant circulating human antibody and also the scaffold for many therapeutic monoclonal antibodies (mAbs). The destruction of IgG-coated targets by cell-mediated pathways begins with an interaction between the IgG Fc region and multiple varieties of membrane-bo...
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| Опубликовано в: : | MAbs |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Taylor & Francis
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5098437/ https://ncbi.nlm.nih.gov/pubmed/27492264 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2016.1218586 |
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