Chromosome 8p tumor suppressor genes SH2D4A and SORBS3 cooperate to inhibit interleukin-6 signaling in hepatocellular carcinoma

Several chronic inflammatory liver diseases, e.g. chronic hepatitis B or C viral infection and steatohepatitis, have been shown to predispose to the development of hepatocellular carcinoma (HCC). In patients with chronic liver disease, interleukin-6 (IL-6) serum levels are elevated and increase even...

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Bibliographic Details
Published in:Hepatology
Main Authors: Ploeger, Carolin, Waldburger, Nina, Fraas, Angelika, Goeppert, Benjamin, Pusch, Stefan, Breuhahn, Kai, Wang, Xin Wei, Schirmacher, Peter, Roessler, Stephanie
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5098049/
https://ncbi.nlm.nih.gov/pubmed/27311882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.28684
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