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Prohibitin, STAT3 and SH2D4A physically and functionally interact in tumor cell mitochondria

Chromosome 8p is frequently deleted in various cancer entities and has been shown to correlate with poor patient survival. SH2D4A is located on chromosome 8p and prevents the nuclear translocation of the pro-tumorigenic transcription factor STAT3. Here, we investigated the interaction of SH2D4A and...

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Détails bibliographiques
Publié dans:Cell Death Dis
Auteurs principaux: Ploeger, Carolin, Huth, Thorben, Sugiyanto, Raisatun Nisa, Pusch, Stefan, Goeppert, Benjamin, Singer, Stephan, Tabti, Redouane, Hausser, Ingrid, Schirmacher, Peter, Désaubry, Laurent, Roessler, Stephanie
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7705682/
https://ncbi.nlm.nih.gov/pubmed/33257655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-03220-3
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