Prohibitin, STAT3 and SH2D4A physically and functionally interact in tumor cell mitochondria

Chromosome 8p is frequently deleted in various cancer entities and has been shown to correlate with poor patient survival. SH2D4A is located on chromosome 8p and prevents the nuclear translocation of the pro-tumorigenic transcription factor STAT3. Here, we investigated the interaction of SH2D4A and...

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Veröffentlicht in:Cell Death Dis
Hauptverfasser: Ploeger, Carolin, Huth, Thorben, Sugiyanto, Raisatun Nisa, Pusch, Stefan, Goeppert, Benjamin, Singer, Stephan, Tabti, Redouane, Hausser, Ingrid, Schirmacher, Peter, Désaubry, Laurent, Roessler, Stephanie
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7705682/
https://ncbi.nlm.nih.gov/pubmed/33257655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-03220-3
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