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In vitro evaluation of the catalytic activity of paraoxonases and phosphotriesterases predicts the enzyme circulatory levels required for in vivo protection against organophosphate Intoxications
Catalytic scavengers of organophosphates (OPs) are considered very promising antidote candidates for preventing the adverse effects of OP intoxication as stand alone treatments. This study aimed at correlating the in-vivo catalytic efficiency ((k(cat)/K(M))[Enzyme](pl)), established prior to the OP...
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| Publicado no: | Chem Biol Interact |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5097891/ https://ncbi.nlm.nih.gov/pubmed/27163850 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2016.04.039 |
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