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In vitro detoxification of cyclosarin in human blood pre-incubated ex-vivo with recombinant serum paraoxonases
An ex-vivo protocol was developed to assay the antidotal capacity of rePON1 variants to protect endogenous acetylcholinesterase and butyrylcholinesterase in human whole blood against OP nerve agents. This protocol permitted us to address the relationship between blood rePON1 concentrations, their ki...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3190592/ https://ncbi.nlm.nih.gov/pubmed/21807078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxlet.2011.07.017 |
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