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Stereospecific effects of oxygen-to-sulfur substitution in DNA phosphate on ion-pair dynamics and protein-DNA affinity
Oxygen-to-sulfur substitutions in DNA phosphate often enhance affinity for DNA-binding proteins. Our previous studies have suggested that this effect of sulfur substitution of both O(P1) and O(P2) atoms is due to an entropic gain associated with enhanced ion-pair dynamics. In this work, we studied s...
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| Publicado no: | Chembiochem |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5096788/ https://ncbi.nlm.nih.gov/pubmed/27271797 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201600265 |
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