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Coordinated histone H3 methylation and acetylation regulates physiologic and pathologic Fas Ligand gene expression in human CD4+ T cells

Activation-induced Fas Ligand (FasL) mRNA expression in CD4+ T cells is mainly controlled at transcriptional initiation. To elucidate the epigenetic mechanisms regulating physiologic and pathologic FasL transcription, TCR-stimulation responsive promoter histone modifications in normal and alcohol-ex...

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Bibliographic Details
Published in:J Immunol
Main Authors: Ghare, Smita S., Joshi-Barve, Swati, Moghe, Akshata, Patil, Madhuvanti, Barker, David F., Gobejishvili, Leila, Brock, Guy N., Cave, Matthew, McClain, Craig J., Barve, Shirish S.
Format: Artigo
Language:Inglês
Published: 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5096587/
https://ncbi.nlm.nih.gov/pubmed/24899502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400055
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