Acrolein enhances epigenetic modifications, FasL expression and hepatocyte toxicity induced by anti-HIV drug Zidovudine

Zidovudine (AZT) remains the mainstay of antiretroviral therapy against HIV in resource-poor countries; however, its use is frequently associated with hepatotoxicity. Not all HIV patients on AZT develop hepatotoxicity, and the determining factors are unclear. Alcohol consumption and cigarette smokin...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Toxicol In Vitro
Prif Awduron: Ghare, Smita S., Donde, Hridgandh, Chen, Wei-Yang, Barker, David F., Gobejishvilli, Leila, McClain, Craig J., Barve, Shirish S., Joshi-Barve, Swati
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4938746/
https://ncbi.nlm.nih.gov/pubmed/27238871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tiv.2016.05.013
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg