TLR and TNF-R1 activation of the MKK3/MKK6–p38α axis in macrophages is mediated by TPL-2 kinase

Previous studies suggested that Toll-like receptor (TLR) stimulation of the p38α MAP kinase (MAPK) is mediated by transforming growth factor-β-activated kinase 1 (TAK1) activation of MAPK kinases, MKK3, MKK4 and MKK6. We used quantitative mass spectrometry to monitor tumour progression locus 2 (TPL-...

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Bibliografski detalji
Izdano u:Biochem J
Glavni autori: Pattison, Michael J., Mitchell, Olivia, Flynn, Helen R., Chen, Chao-Sheng, Yang, Huei-Ting, Ben-Addi, Hakem, Boeing, Stefan, Snijders, Ambrosius P., Ley, Steven C.
Format: Artigo
Jezik:Inglês
Izdano: Portland Press Ltd. 2016
Teme:
Research Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095906/
https://ncbi.nlm.nih.gov/pubmed/27402796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20160502
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