PARP9 and PARP14 cross-regulate macrophage activation via STAT1 ADP-ribosylation

Despite the global impact of macrophage activation in vascular disease, the underlying mechanisms remain obscure. Here we show, with global proteomic analysis of macrophage cell lines treated with either IFNγ or IL-4, that PARP9 and PARP14 regulate macrophage activation. In primary macrophages, PARP...

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書誌詳細
出版年:Nat Commun
主要な著者: Iwata, Hiroshi, Goettsch, Claudia, Sharma, Amitabh, Ricchiuto, Piero, Goh, Wilson Wen Bin, Halu, Arda, Yamada, Iwao, Yoshida, Hideo, Hara, Takuya, Wei, Mei, Inoue, Noriyuki, Fukuda, Daiju, Mojcher, Alexander, Mattson, Peter C., Barabási, Albert-László, Boothby, Mark, Aikawa, Elena, Singh, Sasha A., Aikawa, Masanori
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2016
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5095532/
https://ncbi.nlm.nih.gov/pubmed/27796300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12849
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