The impact of PARPs and ADP-ribosylation on inflammation and host–pathogen interactions

Poly-adenosine diphosphate-ribose polymerases (PARPs) promote ADP-ribosylation, a highly conserved, fundamental posttranslational modification (PTM). PARP catalytic domains transfer the ADP-ribose moiety from NAD(+) to amino acid residues of target proteins, leading to mono- or poly-ADP-ribosylation...

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Dades bibliogràfiques
Publicat a:Genes Dev
Autors principals: Fehr, Anthony R., Singh, Sasha A., Kerr, Catherine M., Mukai, Shin, Higashi, Hideyuki, Aikawa, Masanori
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2020
Matèries:
Special Section: Review
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7050484/
https://ncbi.nlm.nih.gov/pubmed/32029454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.334425.119
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