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The impact of PARPs and ADP-ribosylation on inflammation and host–pathogen interactions
Poly-adenosine diphosphate-ribose polymerases (PARPs) promote ADP-ribosylation, a highly conserved, fundamental posttranslational modification (PTM). PARP catalytic domains transfer the ADP-ribose moiety from NAD(+) to amino acid residues of target proteins, leading to mono- or poly-ADP-ribosylation...
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| Gepubliceerd in: | Genes Dev |
|---|---|
| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Cold Spring Harbor Laboratory Press
2020
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7050484/ https://ncbi.nlm.nih.gov/pubmed/32029454 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.334425.119 |
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